Biocompatible titanium-based alloys for medical prosthetics from complex microalloyed systems
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Project Details
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Design, elaboration and investigation of new, original biocompatible alloy systems, the new variant of alloys contains different values of the alloying percentage of non-toxic elements (Mo and Si) in order to improve the mechanical properties (mechanical strength, modulus of elasticity), alloys that have a good corrosion resistance and biocompatibility corresponding to.
Project Coordinator
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Specific objectives:
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- Designing, obtaining, and testing of Ti-Mo-Si type alloys for medical applications, with the ultimate goal of promoting a new generation of titanium alloys;
- Employing 2 young researchers with full time (TUIASI și INCDFT-IFT IAȘI);
- In vitro biocompatibility study, implantation, osteointegration study, and resorption rate on animal experimental model;
- Testing and complete characterization of biomaterials obtained for patenting;
- Dissemination of results, attracting the interest of implant manufacturers to create medical devices from the new alloy system.
Results
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- Obtaining and structural characterization of at least eight Ti-based alloys with Mo and Si alloys with medical applications;
- Determination of functional properties and biocompatibility in vitro and in vivo of orthopedic alloys in the Ti-Mo-Si system;
- Evaluation of experimental results on the Ti-Mo-Si alloy system;
- Identifying an optimal Ti-Mo-Si ideal composition for orthopedic implants and identifying a global composition of the Ti-Mo-Zr-Ta-Si complex system;
- Publication of at least 6 articles in ISI-indexed journals, development of at least two new patents and participation in international exhibitions, fairs and salons of research.
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